
Proteostasis is the balance between protein production, folding, and degradation. As we age, this balance is disrupted. Misfolded or damaged proteins accumulate, forming toxic aggregates that cells struggle to clear. This is seen in neurodegenerative diseases like Alzheimer's. Additionally, the efficiency of protein-degrading systems like the ubiquitin-proteasome system and autophagy declines, further compromising cellular health.
Essential Longevity ingredients that interact with loss of proteostasis:
- Lion's Mane Mushroom
- Chaga Mushroom
- Agaricus Mushroom
- Quercetin
- Hyaluronic Acid (as Sodium Hyaluronate)
- Glycine
- Taurine
- Vitamin D3
- Vitamin C
- Vitamin B12
- Nicotinamide
- Beta-Glucans (1,3 1,6)
- Phosphatidylcholine
- Cinnamon
- MCT Oil
- Choline
